The Advanced Manufacturing laboratory is a technological hub providing scientific support for a broad range of bio-based businesses as they adapt to Industry 4.0 and beyond. The research staff and equipment provide a unique foundation for the development of prototype software and hardware solutions that solve technical and theoretical problems associated with digital transformation. It includes digitalization of processes and quality-driven value chains as well as production engineering, modelling of complex systems and their optimization. The mechatronic development facility supports prototyping scanning systems for in-line characterization of biomaterials, as well as CNC additive/extractive manufacturing solutions adopted for bio-based technologies. A comprehensive set of hardware components allows rapid prototyping and demonstration for next generation automation of production processes including flexible collaborative robotics.